Saturday 22 June 2013

Do not treat mild hypertension with low risk for heart disease

The benefit from antihypertensive therapy is unproven in patients with mild hypertension and no preexisting cardiovascular disease. 

A meta-analysis combined four placebo-controlled trials adding together 8912 patients with mild hypertension and no preexisting cardiovascular disease.

Up to 5 years of follow-up, antihypertensive therapy resulted in lower rates of mortality and stroke but higher rates of heart attacks.

Low-risk patients with mild hypertension and no preexisting cardiovascular disease who fail to reduce their blood pressure with lifestyle modification should receive antihypertensive therapy.

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